Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02023 |
CD46 Protein, Human, Recombinant (His)
AHUS2,MIC10,CD46 molecule, co... |
Human | HEK293 Cells |
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic... | |||
TMPY-03863 |
CAPG Protein, Human, Recombinant
capping protein (actin filament), gelsolin-like,HEL... |
Human | E. coli |
CAPG, also known as actin Regulatory Protein CAPG, is a a member of the gelsolin/villin family. Members of this family are actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG may also play an important role in macrophage function. | |||
TMPK-00570 |
CD46 Protein, Canine, Recombinant (His)
CD46,AHUS2,TRA2.10,LOC609365,TLX,MCP,MIC10... |
Canine | HEK293 Cells |
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells w... | |||
TMPK-00532 |
CD46 Protein, Cynomolgus, Recombinant (His)
CD46,MCP,TLX,MIC10,AHUS2,TRA2.10 |
Cynomolgus | HEK293 Cells |
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cel... |